Human immunodeficiency virus infected patient with cerebral infarction without non-infectious comorbidities

Authors

  • Ogek Dwi Shavitri Department of Internal Medicine, Wangaya Regional Hospital, Denpasar, Bali, Indonesia
  • Ketut Suryana Department of Internal Medicine, Wangaya Regional Hospital, Denpasar, Bali, Indonesia

DOI:

https://doi.org/10.18203/2349-3933.ijam20243758

Keywords:

Human immunodeficiency virus, Stroke, ART, Cerebral infarction

Abstract

Human immunodeficiency virus (HIV) has been proven to increase the risk of stroke. The annual incidence rate of ischemic stroke in HIV was 216 per 100,000. Multiple factors, linked to HIV infection, could increase the susceptibility of developing cerebrovascular diseases (CVD), such as opportunistic infections, coagulation abnormalities, dyslipidemia, and toxicity of antiretroviral therapy (ART). HIV is thought to contribute to the incidence of stroke through both HIV-associated and traditional stroke risk factors. ARTs, namely protease inhibitors and nucleoside reverse transcriptase inhibitors, can increase the incidence of stroke.

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References

Restrepro L. Stroke and HIV Infection. Department of Neurology Johns Hopkins Hospital Baltimore, Md. 2024. Available at: https://www.ahajournals. org/doi/pdf/10.1161/01.str.0000092895.60959.5d. Accessed on 05 August 2024.

Bogorodskaya M, Chow FC, Triant VA. Stroke in HIV. Canad J Cardiol. 2019;35(3):280-7.

Sadiq E, Katzew S, Nel J, Tade G, Woodiwiss A, Norton G, et al. Stroke, HIV and the Immune Reconstitution Inflammatory Syndrome in the absence of opportunistic infections. J Neurol Sci. 2024;457:122880.

Patel UK, Malik P, Li Y, Habib A, Shah S, Lunagariya A, et al. Stroke and HIV-associated neurological complications: A retrospective nationwide study. J Med Virol. 2021;93(8):4915-29.

Kroon L, van Zyl DG, Schutte CM, Smit C, Hiesgen J. Risk Factors for Stroke in HIV-Positive and-Negative Patients in Pretoria, South Africa. J Stroke Cerebrovasc Dis. 2021;30(8):105929.

Ismael S, Moshahid Khan M, Kumar P, Kodidela S, Mirzahosseini G, Kumar S, et al. HIV Associated Risk Factors for Ischemic Stroke and Future Perspectives. Int J Mol Sci. 2020;21(15):5306.

Bertrand L, Méroth F, Tournebize M, Leda AR, Sun E, Toborek M. Targeting the HIV-infected brain to improve ischemic stroke outcome. Nat Commun. 2019;10(1):2009.

Abdallah A, Chang JL, O'Carroll CB, Musubire A, Chow FC, Wilson AL, et al. Stroke in Human Immunodeficiency Virus-infected Individuals in Sub-Saharan Africa (SSA): A Systematic Review. J Stroke Cerebrovasc Dis. 2018;27(7):1828-36.

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Published

2024-11-30

How to Cite

Shavitri, O. D., & Suryana, K. (2024). Human immunodeficiency virus infected patient with cerebral infarction without non-infectious comorbidities. International Journal of Advances in Medicine, 12(1), 94–96. https://doi.org/10.18203/2349-3933.ijam20243758