Kleine-Levin syndrome: a case report
Keywords:
KLS, Sleep disorders, Periodic hypersomniaAbstract
Kleine-Levin syndrome is characterized as a periodic hypersomnia crisis as well as dietary and variable significant psychiatric symptoms. This case report is of 15 year boy who presented with characterstic features of hypersomnia, hyperphagia, affective features like irritability and cognitive disturbances in an episodic manner with spontaneous remission. Due to the above clinical presentation we made the diagnosis of Kleine-Levin syndrome in this patient who was started on psychostimulant and responded well on these medications.
References
Kleine W. Periodische schlafsucht. Monats Psychiatr Neurol. 1925;57:285-320.
Levin M. Periodic somnolence and morbid hunger: a new syndrome. Brain. 1936;59:494-594.
American Academy of Sleep Medicine. Diagnostic and coding manual. In: AASM, eds. International Classification of Sleep Disorders. 3rd ed. Westchester, Illinois: American Academy of Sleep Medicine; 2013.
Critchely M. Periodic hypersomnia and megaphagia in adolescent males. Brom.1962;8S:627-56.
Lishman WA. The psychological consequences of cerebral disorder. In: Lishman WA, eds. Organic Psychiatry. 3rd ed. US: Blackwell Sciences Ltd.; 1998: 723-733.
Arnulf I, Zeitzer J, File J, Farber N, Mignot E. Kleine-Levin syndrome: a systematic review of 186 cases in the literature. Brain.2005;128:2763-76.
Duffy JP, Davison K. A female case of the Kleine-Levin syndrome. Br J Psychiatry.1968;114:77-84.
Max H, Rhoda GS, Amir S. Sleep disorders. In: Sadock BJ, Sadock VA, Ruiz P, eds. Kaplan & Sadock’s Comprehensive Text Book of Psychiatry, 9th ed. In: Philadelphia: Lippincott William and Lippincott Wilkins; 2007: 2151-2177.
Gallinek A. Syndromes of episodic hypersomnia, bulimia and abnormal mental states. JAMA.1954;154:1081-3.
