Xanthoma disseminatum

Authors

  • Deepak Sharma Department of Dermatology, Era’s Lucknow Medical College, Lucknow, Uttar Pradesh, India
  • Nikha Garg Department of Dermatology, Era’s Lucknow Medical College, Lucknow, Uttar Pradesh, India
  • Tarunveer Singh Department of Dermatology, Era’s Lucknow Medical College, Lucknow, Uttar Pradesh, India
  • Kanwarjit S. Dhillon Department of Dermatology, Era’s Lucknow Medical College, Lucknow, Uttar Pradesh, India
  • Nishi Tandon Department of Pathology, Era’s Lucknow Medical College, Lucknow, Uttar Pradesh, India
  • Mohd Sadiq Umar Department of Dermatology, Era’s Lucknow Medical College, Lucknow, Uttar Pradesh, India
  • Vidhi Agrawal Department of Dermatology, Era’s Lucknow Medical College, Lucknow, Uttar Pradesh, India
  • Ritika Srivastava Department of Dermatology, Era’s Lucknow Medical College, Lucknow, Uttar Pradesh, India

Keywords:

Xanthoma, Non-Langerhans cell hisiocytosis, Diabetes insipidus

Abstract

Xanthoma disseminatum is a rare, benign, normolipemic form of non-Langerhans cell histiocytosis affecting the skin and mucous membranes. The cutaneous manifestations consist of hundreds of papules that are red – brown at first and then become yellowish. The papules symmetrically involve the eyelids, trunk, face and proximal extremities and in flexures and folds, tend quickly to merge, forming soft plaques. It is frequently associated with diabetes insipidus. Biopsy specimens show a mixture of histiocytes, foam cells, and inflammatory cells. Later, foam cells predominate and Touton giant cells are frequently present. This chronic disease has no known established treatment.

References

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Published

2017-02-10

Issue

Vol. 2 No. 1 (2015): January-March 2015

Section

Case Reports