Transthoracic echocardiography as a diagnostic tool in the identification of saddle pulmonary thromboembolism
DOI:
https://doi.org/10.18203/2349-3933.ijam20252536Keywords:
Computed tomography pulmonary angiogram, Pulmonary thromboembolism, Transthoracic echocardiography, Point of care ultrasound, Saddle thrombusAbstract
Pulmonary thromboembolism (PTE) is a common and potentially fatal emergency that results from thrombi mostly originating from deep veins of lower limbs. It is the third most frequent cause of death after myocardial infarction and stroke, with wide clinical spectrum ranging from asymptomatic emboli to sudden death. A particularly severe variant is saddling pulmonary embolism, defined by large thrombus lodges at bifurcation of main pulmonary trunk. Computed tomography pulmonary angiography (CTPA) remains the gold standard for diagnosing PTE. However, its use may be limited by hemodynamic instability, contrast allergies, renal impairment, or unavailability in resource-limited settings. In such scenarios a reliable bedside diagnostic alternative becomes essential. Given the urgency of diagnosis in saddle PTE and limitations of CTPA in critical care settings, echocardiography may serve as an important adjunct in early detection and triage.
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References
Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, et al. The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC). Eur Respir J. 2019;54(3):1901647. DOI: https://doi.org/10.1183/13993003.01647-2019
Rivera-Lebron B, McDaniel M, Ahrar K, Alrifai A, Dudzinski DM, Fanola C, et al. Diagnosis, Treatment and follow up of acute pulmonary Embolism: Consensus Practice from the PERT Consoritum. Clin Appl Thromb Hemost. 2019;25:1076029619853037. DOI: https://doi.org/10.1177/1076029619853037
Jaff MR, McMurtry MS, Archer SL, Cushman M, Goldenberg N, Goldhaber SZ, et al. Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association. Circulation. 2011;123(16):1788-830. DOI: https://doi.org/10.1161/CIR.0b013e318214914f
Kasper W, Konstantinides S, Geibel A, Olschewski M, Heinrich F, Grosser KD, et al. Management strategies and determinants of outcome in acute major pulmonary embolism: results of a multicenter registry. J Am Coll Cardiol. 1997;30(5):1165-71. DOI: https://doi.org/10.1016/S0735-1097(97)00319-7
Wendelboe AM, Raskob GE. Global Burden of Thrombosis: Epidemiologic Aspects. Circ Res. 2016;118(9):1340-7. DOI: https://doi.org/10.1161/CIRCRESAHA.115.306841
Kanjanauthai S, Couture LA, Fissha M, Gentry M, Sharma GK. Saddle pulmonary embolism visualized by transthoracic echocardiography. J Am Coll Cardiol. 2010;56:e21. DOI: https://doi.org/10.1016/j.jacc.2009.10.097
Secko M, Legome E, Rinnert S. Saddle embolism diagnosed by point-of-care transthoracic echocardiography before computed tomography angiogram of the chest. Am J Emerg Med. 2016;34:2467. DOI: https://doi.org/10.1016/j.ajem.2016.06.037
Letourneau MM, Wilczynski S, Rao S, Osman A. Two-for-One saddles: a case of mobile double pulmonary embolism. CASE (Phila). 2018;2:66-8. DOI: https://doi.org/10.1016/j.case.2017.09.011
Pandompatam G, Qaseem M. A 55-year-old man with progressive shortness of breath. Chest. 2022;162:e321-3. DOI: https://doi.org/10.1016/j.chest.2021.12.676
Rudski LG, Lai WW, Afilalo J, Hua L, Handschumacher MD, Chandrasekaran K, et al. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J Am Soc Echocardiogr. 2010;23:685-713. DOI: https://doi.org/10.1016/j.echo.2010.05.010
Pruszczyk P, Torbicki A, Kuch-Wocial A, Szulc M, Acho R. Diagnostic value of transoesophageal echocardiography in suspected haemodynamically significant pulmonary embolism. Heart. 2001;85:628-34. DOI: https://doi.org/10.1136/heart.85.6.628
Fields JM, Davis J, Girson L, Au A, Potts J, Morgan CJ, et al. Transthoracic echocardiography for diagnosing pulmonary embolism: a systematic review and meta- analysis. J Am Soc Echocardiogr. 2017;30:714-23. DOI: https://doi.org/10.1016/j.echo.2017.03.004
Nasser MF, Jabri A, Limaye S, Sharma S, Hamade H, Mhanna M, et al. Echocardiographic evaluation of pulmonary embolism: a review. J Am Soc Echocardiogr. 2023;36:906-12. DOI: https://doi.org/10.1016/j.echo.2023.05.006
Casazza F, Bongarzoni A, Capozi A, Agostoni O. Regional right ventricular dysfunction in acute pulmonary embolism and right ventricular infarction. Eur J Echocardiogr. 2005;6:11-4. DOI: https://doi.org/10.1016/j.euje.2004.06.002
Burnside PR, Brown MD, Kline JA. Systematic review of emergency physician- performed ultrasonography for lower extremity deep vein thrombosis. Acad Emerg Med. 2008;15:493-8. DOI: https://doi.org/10.1111/j.1553-2712.2008.00101.x