Zika virus in northern Kerala: a case report

Authors

  • Bhargavan Pallivalappil Department of General Medicine, BMH, Calicut, Kerala, India
  • Anjana Nair Ayyappanath BMH, Calicut, Kerala, India
  • Thabsheer Sadath Edassery BMH, Calicut, Kerala, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20253357

Keywords:

Zika virus, Flavi virus, Northern Kerala

Abstract

Being a tropical country, emerging Zika virus infection is a major concern in India. In India, the first case of confirmed Zika virus disease was reported from Gujarat. In Kerala, the first Zika Virus outbreak was reported in June 2021 in the southern district of Thiruvananthapuram. Till now there have been no documented reports in the literature about the Zika virus disease in the northern part of Kerala. Hence, we are reporting a 44-year-old lady with fever, maculopapular rash, arthralgia, retro auricular lymphadenitis, gingivitis and bleeding manifestations who on evaluation had anemia, thrombocytopenia and was later diagnosed to have Zika virus infection along with Vitamin B12 deficiency in Tellichery in the northern part of Kerala. This case serves as a reminder of the ongoing threat of emerging infectious diseases in tropical regions and the need for early detection.

Metrics

Metrics Loading ...

References

Nugent EK, Nugent AK, Nugent R, Nugent K. Zika virus: epidemiology, pathogenesis and human disease. The American journal of the medical sciences. 2017 May 1;353(5):466-73. DOI: https://doi.org/10.1016/j.amjms.2016.12.018

Dick GWA, Kitchen SF, Haddow AJ. Zika virus. I. Isolations and serological specificity. Trans R Soc Trop Med Hyg. 1952;46(5):509–20. DOI: https://doi.org/10.1016/0035-9203(52)90042-4

Sharma V, Sharma M, Dhull D, Sharma Y, Kaushik S, Kaushik S. Zika virus: an emerging challenge to public health worldwide. Can J Microbiol. 2020;66(2):87–98. DOI: https://doi.org/10.1139/cjm-2019-0331

Khan E, Jindal H, Mishra P, Suvvari TK, Jonna S. The 2021 Zika outbreak in Uttar Pradesh state of India: Tackling the emerging public health threat. Tropical Doctor. 2022;52(4):474-8. DOI: https://doi.org/10.1177/00494755221113285

Landry ML, St. George K. Laboratory Diagnosis of Zika Virus Infection. Archives of Pathology & Laboratory Medicine. 2016;141(1):60–7. DOI: https://doi.org/10.5858/arpa.2016-0406-SA

Ioos S, Mallet HP, Leparc Goffart I, Gauthier V, Cardoso T, Herida M. Current Zika virus epidemiology and recent epidemics. Médecine et Maladies Infectieuses. 2014;44(7):302–7. DOI: https://doi.org/10.1016/j.medmal.2014.04.008

Song BH, Yun SI, Woolley M, Lee YM. Zika virus: History, epidemiology, transmission, and clinical presentation. J Neuroimmunol. 2017;308:50–64. DOI: https://doi.org/10.1016/j.jneuroim.2017.03.001

Rolph MS, Mahalingam S. Zika’s passage to India. Lancet Infect Dis. 2019;19(5):469–70. DOI: https://doi.org/10.1016/S1473-3099(19)30169-0

Yadav PD, Niyas VKM, Arjun R, Sahay RR, Shete AM, Sapkal GN, et al. Detection of Zika virus disease in Thiruvananthapuram, Kerala, India 2021 during the second wave of COVID‐19 pandemic. J Med Virol. 2022;94(6):2346–9. DOI: https://doi.org/10.1002/jmv.27638

Bhardwaj S, Gokhale MD, Mourya DT. Zika virus: Current concerns in India. Indian J Med Res. 2017;146(5):572. DOI: https://doi.org/10.4103/ijmr.IJMR_1160_17

Downloads

Published

2025-10-24

How to Cite

Pallivalappil, B., Ayyappanath, A. N., & Edassery, T. S. (2025). Zika virus in northern Kerala: a case report. International Journal of Advances in Medicine, 12(6), 606–609. https://doi.org/10.18203/2349-3933.ijam20253357