Musculoskeletal disorders in patients with diabetes mellitus: a neglected manifestation
DOI:
https://doi.org/10.18203/2349-3933.ijam20261088Keywords:
Musculoskeletal disorders, Diabetes mellitus, Diabetes complications, Frozen shoulder, Osteoporosis, OsteoarthritisAbstract
Background: A variety of musculoskeletal manifestations are commonly related with diabetes mellitus. This study is aimed at evaluating the prevalence and clinical spectrum of musculoskeletal manifestations in patients with diabetes mellitus in KJ Somaiya Hospital, Mumbai.
Methods: A tertiary care centre based cross-sectional study was conducted with 82 patients from November 2018 to October 2020 to evaluate the pattern of musculoskeletal (MSK) manifestations in adult diabetic patients and to correlate them with duration and control of diabetes. A detailed history and clinical examination were noted in each patient with particular importance given on musculoskeletal examination and relevant investigations.
Results: Most of the patients (35.6%) were aged between 51 and 60 years. Female patients accounted for 63.4% of the study population. 69 (84.2%) patients had HbA1c ≥7 (poor glycaemic control). The most common musculoskeletal manifestation was Frozen shoulder (18.3%) followed by Osteoarthritis (17.1%).
Conclusions: Musculoskeletal manifestations are quite prevalent in patients with diabetes mellitus, and there is significant correlation between development of these manifestations and glycaemic control, age and duration of diabetes of patients.
References
Wild S, Roglic G, Green A. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 2004;27:1047-53.
International Diabetes Federation. IDF Diabetes Atlas. 6th ed. Brussels: International Diabetes Federation. 2013.
Maiti S, Akhtar S, Upadhyay AK, Mohanty SK. Socioeconomic inequality in awareness, treatment and control of diabetes among adults in India: Evidence from National Family Health Survey of India (NFHS), 2019–2021. Sci Rep. 2023;13:2971.
International Diabetes Federation. IDF Diabetes Atlas. 10th ed. Brussels: International Diabetes Federation. 2021.
Silva MBG, Skare TL. Manifestações musculoesqueléticas em diabetes mellitus. Rev Bras Reumatol. 2012;52(4):601-9.
Suzuki A, Yabu A, Nakamura H. Advanced glycation end products in musculoskeletal system and disorders. Methods. 2022;203:179-86.
American Diabetes Association. Diabetes Care. 2018;40(1):S13-27.
Sarkar S, Goswami B, Sengupta B, Sengupta S, Bhattacharjee B. Musculoskeletal manifestations in type-2 diabetic patients attending a tertiary care hospital in a North-Eastern city of India-A cross-sectional observational study. J Family Med Prim Care. 2023;12(3):472-7.
Goldin A, Beckman JA, Schmidt AM, Creager MA. Advanced Glycation End Products Sparking the Development of Diabetic Vascular Injury. Circulation. 2006;114:597-605.
Olson LC, Redden JT, Schwartz Z, Cohen DJ, McClure MJ. Advanced Glycation End-Products in Skeletal Muscle Aging. Bioengineering (Basel). 2021;8(11):168.
Jobin P, Dhurvey P, Nair A. Prevalence of musculoskeletal manifestations in patients with type 2 Diabetes mellitus in a tertiary care hospital. Indian J res. 2018;7(8):38-41.
Majjad A, Errahali Y, Toufik H. Musculoskeletal Disorders in Patients with Diabetes Mellitus: A Cross-Sectional Study. Int J Rheumatol. 2018;2018:3839872.
Edis P, Özdemir N, Hekimsoy Z. The musculoskeletal disorders in diabetic patients and the evaluation of their relationship with metabolic parameters and microvascular complications. Acta Endocrinol (Buc). 2024;20(2):136-42.
Ramchurn N, Mashamba C, Leitch E, Arutchelvam V, Narayanan K, Appleyard M. Upper limb musculoskeletal abnormalities and poor metabolic control in diabetes. Eur J Intern Med. 2009;20:123-30.
Downloads
Published
How to Cite
Issue
Section
