Reactive perforating collagenosis

Authors

  • K. S. Dhillon Department of Dermatology, Era’s Lucknow Medical College & Hospital, Lucknow-226003, Uttar Pradesh, India
  • Uroos Fatima Department of Pathology, Era’s Lucknow Medical College & Hospital, Lucknow-226003, Uttar Pradesh, India
  • Isha Singh Department of Dermatology, Era’s Lucknow Medical College & Hospital, Lucknow-226003, Uttar Pradesh, India
  • Tarunveer Singh Department of Dermatology, Era’s Lucknow Medical College & Hospital, Lucknow-226003, Uttar Pradesh, India
  • Tanu Gupta Department of Dermatology, Era’s Lucknow Medical College & Hospital, Lucknow-226003, Uttar Pradesh, India
  • Nawed Khan Department of Dermatology, Era’s Lucknow Medical College & Hospital, Lucknow-226003, Uttar Pradesh, India
  • Krati R. Varshney Department of Microbiology, Era’s Lucknow Medical College & Hospital, Lucknow-226003, Uttar Pradesh, India
  • Rakhee Sharma Department of Gynaecology, Era’s Lucknow Medical College & Hospital, Lucknow-226003, Uttar Pradesh, India

Keywords:

Reactive perforating collagenosis, Diabetes mellitus, Chronic renal failure

Abstract

Reactive Perforating Collagenosis (RPC) is a rare disease of elimination of altered collagen through the epidermis. The disease exists in childhood form with autosomal recessive mode of inheritance and an adult form acquired in association with diseases such as Diabetes Mellitus (DM), Chronic Renal Failure (CRF), hypothyroidism, lymphoma, hyperparathyroidism, neurodermatitis, AIDS, pulmonary fibrosis, scabies and herpes zoster infection.  

References

Mehregan AH, Schwartz OD, Livingood CS. Reactive perforating collagenosis. Arch Dermatol. 1967;96:277-82.

Herzinger T, Schirren CG, Sander CA, Jansen T, Kind P. Reactive perforating collagenosis - transepidermal elimination of type 4 collagen. Clin Exp Dermatol. 1996;21:279-82.

Cullen S. Successful treatment of reactive perforating collagenosis with tretinoin. Cutis. 1979;23:187-91.

Morton CA, Henderson IS, Jones MC, Lowe JG. Acquired perforating dermatosis in a British dialysis population. Br J Dermatol. 1996;135:671-7.

Hoque SR, Ameen M, Holden CA. Acquired reactive perforating collagenosis: four patients with a giant variant treated with allopurinol. Br J Dermatol. 2006;154:759-62.

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Published

2017-02-10

Issue

Section

Case Reports