Frank’s sign: silent predictor of coronary artery disease
Keywords:
Frank’s sign, Coronary artery diseaseAbstract
A 60 year old non hypertensive, non diabetic male presented in casualty with complaints of exertional breathlessness of 2 days duration. ECG and cardiac enzymes were within normal limit. General physical examination was normal except for the finding of bilateral ear lobe creases (Figure 1 & 2). With the possibility of angina equivalent patient was posted for coronary angiography which revealed total occlusion of left anterior descending artery and right coronary artery, 80% obtuse marginal and 70% left circumflex artery. LVEF was 25% and patient was advised for high risk CABG. Creased earlobes (Frank’s sign) were alleged to be associated with an increased risk of coronary artery disease.Metrics
References
Medline Plus. Earlobe creases. Available at http://www.nlm.nih.gov/medlineplus/ency/article/003045.htm. Accessed 19 March 2014.
Constant J. Bedside cardiology, 5th Edition. Lippincott Williams & Wilkins, Wolters Kluwer Company; 2003:20.
Lichtstein E, Chapman I, Gupta PK, Chadda KD, Smith H Jr, Schwartz I, et al. Letter: Diagonal ear-lobe crease and coronary artery sclerosis. Ann Intern Med. 1976 Sep;85(3):337-8.
Elliott WJ, Karrison T. Increased all-cause and cardiac morbidity and mortality associated with the diagonal earlobe crease: a prospective cohort study. Am J Med. 1991 Sep;91(3):247-54.