Stem cell transplantation from a space person in a haematological cancer patient

Debajani Deka; Sanjay Mishra

doi:10.18203/2349-3933.ijam20263732

Authors

Debajani Deka Department of Anatomy, Pragjyotishpur Medical College, Guwahati, Assam, India
Sanjay Mishra AIIMS, Jammu, Jammu and Kashmir, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20263732

Keywords:

Stem cell , Cancer, Epigenetic

Abstract

Epigenetic changes are a reversible process. The epigenetic changes are: methylation, histone modification, and non-coding RNA. Through processes such as DNA methylation, histone modification and non-coding RNA action, the chromatin state is altered, thereby influencing gene activation. Moreover, epigenetic modifications can respond to environmental exposures. DNA methylation typically silences genes by adding methyl groups to cytosine bases neighbouring guanines; chemical modifications in histone tails can either loosen or tighten DNA winding around histones, affecting accessibility to transcription factors; and non-coding RNAs can interfere with transcription or translation processes.

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