Acute acalculous cholecystitis in dengue fever patients

Authors

  • Manish Chandey Department of Medicine, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India
  • Harjot Kaur Department of Pathology, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India
  • Sukhjeet Kaur Department of Biochemistry, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20170923

Keywords:

Acalculous cholecystitis, Dengue fever

Abstract

Background: Dengue fever is an acute febrile illness characterized by frontal headache, retro ocular pain, muscle and joint pain, nausea, vomiting and rash. Frequent sonographic findings in a case of dengue include thickened gall bladder with pericholecystitic fluid, ascites, spleenomegaly and pleural effusion which is commonly right sided.

Methods: 540 patients of confirmed dengue fever were subjected to ultrasonography abdomen to find the incidence of acalculous cholecystitis for diagnostic and prognostic significance.

Results: Acalculous cholecystitis was detected in 210 patients (38.88%) of confirmed dengue fever. Patients developing acalculous cholecystitis recovered with conservative treatment only though the hospital stay was prolonged in these patients.

Conclusions: In dengue fever patients, acute acalculous cholecystitis is not uncommon and is usually self-limiting and resolves with conservative management only. Role of ultrasonography has a supporting role in dengue fever for prognostic and diagnostic significance.

Author Biographies

Manish Chandey, Department of Medicine, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India

Associate Professor

Department of Medicine

Harjot Kaur, Department of Pathology, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India

Deartment of Pathology

Sukhjeet Kaur, Department of Biochemistry, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India

Department of Biochemistry

References

Khan E, Siddiqui J, Shakoor S, Mehraj V, Jamil B, Hasan R. Dengue outbreak in Karachi, Pakistan, 2006: experience at atertiary care centre. Trans R soc Trop Med Hyg. 2007;101:1114-9.

Halstead SB. Dengue hemorrhagic fever: a public health problem and a field for research. Bull. 1980;581:1-21.

Kalayanarooj S, Vaughn DW, Nimmannitya S, Green S, Suntayakorn S, Kunentrasai N, et al. Early clinical and laboratory indicators of acute dengue illness. J Infect Dis. 1997;176:313-21.

Cobra C, Rigau PZ, Kuno G, Vorndam V. Symptoms of dengue fever in relation to host immunologic response and virus serotype, Puerto Rico,1990-1991. Am J Epidemiol. 1995;142:1204-11.

Sood A, Midha V, Sood N, Kausha V. Acalculuos cholecysytitis as an atypical presentation of dengue fever. Am J Gastroenterol. 2000;95(2):3316-7.

George R, Liam CK, Chua CT, Lam SK, Pam T, Geethan R, et al. Unusual clinical manifestations of dengue virus infection. South east Asian J Trop Med Public Health. 1988;19:585-90.

Nimmannitya S, Thisyakorn U, Hemrichant V. Dengue haemorrhagic fever with unusual manifestations. South East Asian J trop Med. 1987;18:398-406.

Venkata PM, Krishnan R. Role of ultrasound in dengue fever. British J Radiol. 2005;78:416-8.

Thulkar S, Sharma S, Shrivastva DN, Sharma SN, Berry M. Sonography findings in grade III dengue hemorrhagic fever in adults. J Ultraosound. 2000;28(1):34-7.

Wu KL, Chang CCS, Kuo CH. Early abdominal sonographic findings in patients with dengue fever. J Clin Ultrasound. 2004;32(8):386-8.

Prasad A, Yasmeen M, Prasad GS. Study of acute acalculuos cholecystitis as an atypical manifestation in dengue fever. Int J Med Sci Public Health. 2015;4:1231-4.

Gulati S, Maheshwari A. Atypical manifestations of dengue. Trop Med Int Health. 2007;12(9):1087-95.

Shapiro MJ, Luchtefeld WB, Kurzweil S, Kaminski DL, Durham RM, Mazuski JE. Acute acalculuos cholecystitis in the critically ill. Am Surg. 1994;60:335-9.

Gubler DJ, Kun G, Sather GE, Velez M, Oliver A. Mosquito cell cultures and specific monoclonal antibodies in surveillance for dengue virus. Am J Trop Med Hyg. 1984;33:158-65.

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Published

2017-03-23

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Original Research Articles