Clinico-pathological study of primary carcinoma of the liver
Keywords:Cirrhosis, Histopathology, Primary carcinoma of the liver
Background: Since the incidence of the primary carcinoma of the liver in Warangal is very high when compared to other parts of the country, the possible etiological factors have been studied for the increasing frequency of Primary carcinoma of the liver with a view for further follow up. The objective of the present study was to undertake a thorough study of histopathological changes, typing and its association with cirrhosis.
Methods: A hospital based cross sectional study was carried for a period of three years among 56 cases of primary carcinoma of the liver at MGM hospital. Institutional Ethics Committee permission was obtained. Informed consent was taken from each and every patient. Detailed history, clinical examination and investigations were carried out for each and every included patient. Liver biopsy was done under strict aseptic precautions.
Results: The incidence of Primary carcinoma of the liver was found to be highest in males as compared to females. The highest incidence of Primary carcinoma of the liver was found in the age group of 41-50 years. In only 14.3% of cases the Primary carcinoma of the liver was associated with cirrhosis of liver. The most common type of cell found on histopathology was cylindroids type in 35.7% of cases followed by trabecular type in 28.5% of cases.
Conclusions: Incidence of Primary carcinoma of the liver was found to be very high. This was not associated with corresponding increase in cirrhosis. The cause of their increase was obscure.
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