Recurrent self-healing painful ecchymoses and fever: a case of Gardner-diamond syndrome

Authors

  • Sachanidou M. G. Department of Skin and Venereal Diseases, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece
  • Arampatzis G. D. Department of Skin and Venereal Diseases, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece
  • Zioga A. Department of Pathology Laboratory, University Hospital of Ioannina, Ioannina, Greece
  • Gaitanis G. 1Department of Skin and Venereal Diseases, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece 2Department of Dermatology, University Hospital of Ioannina, Ioannina, Greece
  • Ioannis D. Bassukas 1Department of Skin and Venereal Diseases, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece 2Department of Dermatology, University Hospital of Ioannina, Ioannina, Greece

DOI:

https://doi.org/10.18203/2349-3933.ijam20171066

Keywords:

Erythrocyte autosensitization test, Eryptosis, GDS

Abstract

Gardner - Diamond syndrome (GDS) is a rare recurrent condition of painful ecchymoses without apparent eliciting factors. We report a 40-year old woman with GDS without psychiatric comorbidity. She presented with, recurrent episodes of spontaneous, self-limiting corps of painful ecchymotic bruising and fever. Her medical history, physical and psychiatric examinations, a focused imaging work up and bone marrow biopsy were unremarkable; the skin biopsy excluded vasculitis. However, the erythrocyte autosensitization test was positive; a finding that together with history and clinico-laboratory results highly suggests GDS.

References

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Ivanov OL, Lvov N, Michenko V, Künzel J, Mayser P, Gieler U. Autoerythrocyte sensitization syndrome (Gardner-Diamond syndrome): review of the literature. J Eur Acad Dermatol Venereol. 2009;23:499-504.

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Published

2017-03-23

Issue

Vol. 4 No. 2 (2017): March-April 2017

Section

Case Reports