DOI: http://dx.doi.org/10.18203/2349-3933.ijam20171061

Spectrum of primary epithelial tumors of major salivary glands: a 5 year record based descriptive study from a tertiary care centre

Jayalakshmy Payippat Leelamma, Bhavya P. Mohan

Abstract


Background: Salivary gland tumors constitute a highly heterogeneous histopathologic group. There are few epidemiological studies of large series of benign and malignant epithelial tumors of major salivary glands in South India.

Methods: This is a retrospective study in a tertiary care centre in Kerala, South India. A total of 180 epithelial neoplasms of major salivary gland were studied over a 5 year period. In each case age, sex, anatomical location and histopathological diagnosis were recorded.

Results: Patients with benign and malignant tumors presented with a mean age of 52.3 and 55.9 years respectively. The frequency of benign tumors was 80.6% (n = 145) and of malignant tumors was 19.4% (n = 35). There was a higher prevalence of tumors in males 60.6% (n = 109) than in females 39.4% (n = 71). 91.9% (n = 164) of the tumors were localized in the parotid gland, 8.3% (n = 15) in the submandibular gland and 0.6% (n = 1) in the sublingual gland. The most common benign tumors were Pleomorphic adenoma (48.9%, n = 88) and Warthin’s tumor (28.9%, n = 52). Among malignant tumors, Mucoepidermoid carcinoma was the most common (9.5%, n = 17) followed by Carcinoma ex pleomorphic adenoma (2.8%, n = 5) and adenoid cystic carcinoma (2.2%, n = 4).

Conclusions: Parotid gland was the most common site of both benign and malignant tumours. Plemorphic adenoma was the most common benign tumor and mucoepidermoid carcinoma was the most common malignant tumor.

Keywords


Epidemiology, Epithelial, Heterogeneous, South India, Salivary gland

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