Published: 2017-01-23

Prevalence and morphological patterns of tuberculosis in various organs

Minali Raja, . Tanvi, Harish Chaturvedi, Aditi Chaturvedi


Background: Tuberculosis (TB) is a common and often deadly infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis in humans. A third of the world's population is thought to be infected with M. tuberculosis and new infections occur at a rate of about one per second. The present study aimed to study the prevalence of TB in various organs.

Methods: This was both prospective and retrospective study and a total of 14,472 patients of all ages and both the sexes were included in the study. All prospective cases during this period and retrospective cases of past one year i.e. total of 14,472 cases were included in the study. Data was entered in MS-Excel sheet and statistical analysis was done.

Results: Out of 14,472 patients maximum number of cases received in the department were of female genital tract (FGT) infections 3634 (25.11%) followed by gastrointestinal tract (GIT) 2246 (15.51%) and then reticuloendothelial system (RES) 1807 (12.48%). 9471 (65.44%) cases were observed with non-neoplastic lesions and 5001 (34.56%) with neoplastic lesions. The number of inflammatory and tubercular cases with non-neoplastic lesions was 4338. Out of 4338 inflammatory cases, 284 cases were reported with TB in various systems. The maximum cases 86 (30.28%) were seen in the third decade followed by fourth decade 55 (19.36%). Youngest patient was 2 year old while the oldest was 80 years old. Incidence of TB was low in 6th and 7th decade of life.

Conclusions: The incidence of pulmonary and extrapulmonary TB in our study population was significantly high. Hence further investigation was required to determine a proper diagnostic approach of its morphological pattern so that accurate treatment can be opted.


Extra-pulmonary TB, Pulmonary TB, Tuberculosis

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Stuart WJ. Epididymal tuberculosis. Available at Accessed on 18 August 2010.

Vernon MP. Prostatitis, Tuberculous. Available at May 4 2010. Accessed on 18 August 18 2010.

WHO. Profile of high-burden countries. Global Tuberculosis control. WHO report 2009. Available at http://www.C:/Users/COMP/Downloads/tub_ Global % 20 TB% 20 full_report % 202009.pdf. Accessed on 10 January 2016.

Fanning A. Tuberculosis: Extrapulmonary disease. Canadian Med Asso J. 1999;160:1597-603.

Iscman MD. Tuberculosis in relation to human immunodeficiency virus and acquired immunodeficiency syndrome. In: Iseman MD, eds. A clinician’s guide to tuberculosis. Philadelphia: Lippincott Williams and Wilkins; 2000:199-252.

Dutt AK, Stead WW. Epidemiology. In: Schlossberg D, eds. Tuberculois and nontuberculous mycobacterial infection. Philadelphia: W.B. Saunders Company; 1999:3-16.

Gopal R, Padmavathy BK, Vasanthi S, Jayashree K. Extra - pulmonary tuberculosis - a retrospective study. Ind J Tub. 2001;48:225-6.

Standardized treatment regimens. In: Maher D, Chaulet P, Spinaci S, Harries A, eds. Treatment of Tuberculosis: Guidelines for National Programmes. 2nd ed. Geneva, Switzerland: World Health Organization; 1997:25-31.

Gow JG. Genitourinary tuberculosis. In: Walsh PC, Retik AB, Vaughan ED, Wein AJ, eds. Campbell’s Urology. 7th ed. Philadelphia: W.B. Saunders Company; 1998:807-36.

Chakraborty AK. Epidemiology of tuberculosis: current status in India. Indian J Med Res. 2004;120:248-76.

Carl P, Stark L. Indications for surgical management of genitourinary tuberculosis. World J Surg. 1997;21:505-10.

Chakma T, Rao PV, Pall S, Kaushal LS, Datta M, Tiwary RS. Survey of pulmonary tuberculosis in a primitive trible of Madhya Pradesh. Ind J Tub. 1996;43:85-9.

Ariel BM, El'kin AV, Basek TS, Ostashko OM, Katser LI. Morphological features of fibro-cavernous pulmonary tuberculosis according to the surgical material. Arkh Patol. 2004;66(1):14-8.

Vinokurov II, Argunov VA, Nikolaev IuIa, Plotnikova NV. The clinical and morphological features of pulmonary tuberculosis under the conditions of the Far North. Probl Tuberk Bolezn Legk. 2006;7:44-7.

Das DK, Pant CS, Pant JN, Sodhani P. Transthoracic (percutaneous) fine needle aspiration cytology diagnosis of pulmonary tuberculosis. Tubercle and Lung Disease. 1995;76(1):84-9.

Sharma SK, Mohan A. Extrapulmonary tuberculosis. Indian J Med Res. 2004;120:316-53.

Jha BC, Dass A, Nagarkar NM, Gupta R, Singhal S. Cervical tuberculous lymphadenopathy: changing clinical pattern and concepts in management. Postgrad Med J. 2001;77:185-7.

Bhatt JV, Shah JM, Shah F. Clinico-Pathological profile of cervical lymphadenopathy. Available at Accessed on 19 August 2010.

Maharjan M, Hirachan S, Kafle PK, Bista M, Shrestha S, Toran KC, et al. Incidence of tuberculosis in enlarged neck nodes, our experience. Kathmandu Univ Med J. 2009;7(1):54-8.

Singhal A, Gulatia A, Frizellb R, Manninga AP. Abdominal tuberculosis in Bradford, UK: 1992-2002. Eur J Gastroenterol Hepatol. 2005;17:967-71.

Christensen WI. Genitourinary tuberculosis: Review of 102 cases. Medicine (Baltimore). 1974;53:377-90.

Mochalova TP, Starikov IY. Reconstructive surgery for treatment of urogenital tuberculosis: 30 years of observation. World J Surg. 1997;21:511-5.

Sutherland AM. The changing pattern of tuberculosis of the female genital tract. A thirty year survey. Arch Gynaecol. 1983;234:95-101.

Mehrotra R, Sharma K. Cytodiagnosis of tuberculosis of the skull by fine needle aspiration cytology: a case report pathology. 2000;32(3):213-5.

Patra AC, Gharami RC, Banerjee PK. A profile of cutaneous tuberculosis. Indian J Dermatol. 2006;51(2):105-7.

Liu P, Shi ZY, Lau YJ, Hu BS. Rapid diagnosis of tuberculous meningitis by a simplified nested amplification protocol. Neurology. 1994;44:1161-4.

Coller FA, Huggins CB. Tuberculosis of the thyroid gland. Anu Surg. 1926;84:408.