Study of serum lipid profile in stroke patients in Northern India

Authors

  • Onkar Nath Rai Department of Medicine, Government Medical College, Azamgarh, Uttar Pradesh, India
  • Amit Kumar Department of Medicine, Government Medical College, Azamgarh, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20174286

Keywords:

Lipid profile, Stroke

Abstract

Background: Stroke is one of the leading causes of death and disability worldwide. This study was undertaken to establish the role of serum lipid profile in patients of stroke in Northern India.

Methods: The study involved 100 patients of stroke who were admitted to B.R.D. medical college, Gorakhpur. The patients were classified as having ischemic or hemorrhagic stroke definitive on the basis of CT scan of head (plain and contrast). Lipid profile estimation was done.

Results: Out of 100 patients 46 had hemorrhagic stroke and 54 had Ischemic stroke. Abnormal lipid values were found in 54 patients.  Total cholesterol was abnormal in 83% of ischemic stroke and 17% of hemorrhagic stroke. LDL cholesterol was abnormal in 86% of ischemic stroke and 14% of hemorrhagic stroke.

Conclusions: Regular monitor of lipid profile among stroke patients may decrease the risk of atherosclerosis and cardiovascular disease among the stroke patients.

References

Bonita R, Mendis S, Truelsen T, Bogousslavsky J, Toole J, Yatsu F. The global stroke initiative. Lancet Neurol. 2004;3:391-3.

Powers AC. Harrison's Principles of Internal medicine, Cerebrovascular Accident. Maryland. 2012;338:2275-304.

Kirshner HS. Medical prevention of stroke. South Med J. 2003;96:354-8.

Bhalla A, Gupta OP, Gupta SB. Predicting mortality in stroke. Neurol India. 2002;50(3):279-81.

Banerjee TK, Das SK. Fifty years of stroke researches in India. Ann Indian Acad Neurol. 2016;19(1):1-8.

Wasay M, Khatri IA, Kaul S. Stroke in South Asian countries. Nat Rev Neurol. 2014;10:135-43.

Khan J, Attique-ur-Rehman, Ali SA, Jielani A. Frequency of hypertension in stroke patients presenting at Ayub teaching hospital. J Ayub Med Coll Abbottabad. 2006;18(1):59-61.

Sreenivasulu C, Bai LS, Kumar KN. Study of serum lipid profile in stroke patients, medical science. Indian J Applied Res. 2016;6(2):385-6.

Qizilbash N, Duffy SW, War low C, Mann J. Lipids are risk factors for ischemic stroke: overview and review. Cerebrovascular Disease. 1992;3(2):127-36.

Tanveer A. Localization and management in cerebrovascular accident: a comparison of clinical assessment versus CT scan (dissertation). J Coll Physician Surg Pak. 1996:5-6.

Siddeswari R, Sudarsi B, Abhilash T, Rao NS. A study on risk factors and lipid profile pattern in patients of stroke in Osmania general hospital, Hyderabad, India. Int J Res Med Sci. 2015;3:3337-41.

Gnanamoorthy K, Suthakaran PK, Rajendran K, Deepak K. Comparison of fasting lipid profile in ischemic and haemorrhagic stroke patients of a tertiary care hospital. Int J Adv Med. 2016;3:755-8.

Wild SH, Byrne CD, Tzoulaki I, Lee AJ, Rumley A, Lowe GD, et al. Metabolic syndrome, haemostatic and inflammatory markers, cerebrovascular and peripheral arterial disease. Edinburgh Artery Study. Atherosclerosis. 2009;203:604-9.

Sacco RL. Risk factors and outcomes for ischemic stroke. Neurol. 1995;45:S10.

Anthony S, Kim N, S. Claiborne Johnston. Neurologic complications of hypertension. eds. Aminoff’s Neurology and General Medicine. 2nd ed. USA: Academic Press; 1996:1216.

Grundy, Sacco, Anthony S. Kim N, S. Claiborne Johnston. Neurologic complications of hypertension. In: Grundy, Sacco, Anthony S. Kim N, S. Claiborne Johnston, eds. Aminoff’s Neurology and General Medicine. 2nd ed. USA: Academic Press; 1996 and 2004:1216.

Downloads

Published

2017-09-22

Issue

Section

Original Research Articles