Serum C- reactive protein level and lipid profile in periodontitis and coronary artery disease in people of Bhuj region

Dinesh Dave, Vishal Desai


Background: Many epidemiological studies have investigated the relationship between periodontal disease and coronary artery disease but their result is heterogeneous. This review article is designed to update the association between periodontal disease and cardiovascular events. Hence, the aim of the present study was to assess whether there is a link between periodontal and coronary artery disease (CAD).

Methods: This study includes 90 subjects, which were divided into 3 groups: 30 subjects -healthy individuals, 30 subjects- having Periodontitis, 30 subjects-  suffering from coronary artery diseases.

Results: The mean OHI-S scores for group 1, 2 and 3 were 0.95±0.60, 2.91±0.90, 1.54±0.74 respectively. CRP level group 2 and 3 were significantly higher than group 1 (p =0.002 and 0.00 respectively) whereas difference between group 2 and 3 was not significantly significant. Lipid profiles, cholesterol, low density lipoprotein (LDL), triglycerides higher in group 2 as compare to 1 and 3. High density lipoprotein (HDL) levels between groups were not significantly different.

Conclusions: Based on results and other reports Periodontitis may be a risk factor for CAD and possibly there can be an association between periodontal diseases.


C-reactive protein, Coronary artery disease, Lipid metabolism, Periodontitis

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