A case control study in BMC Sagar to identify the risk factors for heart failure in patients with recently diagnosed myocardial infarction

Authors

  • Ramesh Pandey Department of Medicine, Bundelkhand Medical College, Sagar, Madhya Pradesh, India
  • Shikha Pandey Department of Obstetrics and Gynaecology, Bundelkhand Medical College, Sagar, Madhya Pradesh, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20173643

Keywords:

Myocardial infarction, Mortality, Risk factor

Abstract

Background: This study was conducted to identify the risk factors for heart failure (HF) in recently diagnosed myocardial infarction (MI) patients in Bundelkhand region of Madhya Pradesh, India.

Methods: In this hospital-based, case-control study, the participants were all new myocardial infarction patients hospitalized from April 2016 to March 2017 in Bundelkhand Medical College (BMC) and associated hospital Sagar, Madhya Pradesh. There were 1,691 new cases with heart failure and 6,764 patients without heart failure as controls. Controls were selected randomly as per incidence density sampling. Odds ratios (ORs) with a 95% confidence interval (CI) was calculated to identify potential risk factors, using conditional logistic regression models.

Results: The mortality rate was 18.2% in the cases and (12.1%) in the controls (p<0.05). Important risk factors for heart failure were: stroke (OR, 2.00; 95% CI, 1.39 to 2.89), and right bundle branch block (RBBB) (OR, 2.86; 95% CI, 1.95 to 4.19). The factors significantly associated with heart failure Diabetes, hypertension, atrial fibrillation, ventricular tachycardia, and age. Incidence (p<0.05). Significant factor in women was diabetes (OR, 1.41; 95% CI, 1.05 to 1.88) while in men age, hypertension, and RBBB are important.

Conclusions: This study might help to identify and monitor the predictive risk factors for heart failure in myocardial infarction patients. The type of risk factors was different in men and women.

 

Author Biographies

Ramesh Pandey, Department of Medicine, Bundelkhand Medical College, Sagar, Madhya Pradesh, India

MEDICINE

ASSOCIATE PROFESSOR 

Shikha Pandey, Department of Obstetrics and Gynaecology, Bundelkhand Medical College, Sagar, Madhya Pradesh, India

ASSOCIATE PROFFESSOR OBG DEPARTMENT

References

Pillai HS, Ganapathi S. Heart failure in South Asia. Curr Cardiol Rev. 2013;9:102-11.

Brettell R, Soljak M, Cecil E, Cowie MR, Tuppin P, Majeed A. Reducing heart failure admission rates in England 2004-2011 are not related to changes in primary care quality: national observational study. Eur J Heart Fail. 2013;15:1335-42.

Liu LC, Damman K, Lipsic E, Maass AH, Rienstra M, Westenbrink BD. Heart failure highlights in 2012-2013. Eur J Heart Fail. 2014;16:122-32.

Liu L, Eisen HJ. Epidemiology of heart failure and scope of the problem. Cardiol Clin. 2014;32:1-8.

Kannel WB. Vital epidemiologic clues in heart failure. J Clin Epidemiol. 2000;53:229-35.

Heo S, Moser DK, Lennie TA, Fischer M, Smith E, Walsh MN. Modifiable correlates of physical symptoms and health-related quality of life in patients with heart failure: a cross-sectional study. Int J Nurs Stud. 2014;51:1482-90.

Lewis EF, Li Y, Pfeffer MA, Solomon SD, Weinfurt KP, Velazquez EJ, et al. Impact of cardiovascular events on change in quality of life and utilities in patients after myocardial infarction: a VALIANT study (valsartan in acute myocardial infarction). JACC Heart Fail. 2014;2:159-65.

Mendez GF, Cowie MR. The epidemiological features of heart failure in developing countries: a review of the literature. Int J Cardiol. 2001;80:213-9.

Sakata Y, Shimokawa H. Epidemiology of heart failure in Asia. Circ J. 2013;77:2209-17.

Ahmadi A, Soori H, Mehrabi Y, Etemad K, Samavat T, Khaledifar A. Incidence of acute myocardial infarction in Islamic Republic of Iran: a study using national registry data in 2012. East Mediterr Health J. 2015;21:5-12.

Ahmadi A, Soori H, Mehrabi Y, Etemad K, Khaledifar A. Epidemiological pattern of myocardial infarction and modelling risk factors relevant to in-hospital mortality: the first results from the Iranian Myocardial Infarction Registry. Kardiol Pol. 2015;73:451-7.

Eugene Braunwald E, Bonow RO. Braunwald’s heart disease: a textbook of cardiovascular medicine. 9th. Philadelphia: Saunders; 2012:133-134.

Cleland JG, Torabi A, Khan NK. Epidemiology and management of heart failure and left ventricular systolic dysfunction in the aftermath of a myocardial infarction. Heart. 2005;91 Suppl 2:7-13.

Minicucci MF, Azevedo PS, Polegato BF, Paiva SA, Zornoff LA. Heart failure after myocardial infarction: clinical implications and treatment. Clin Cardiol. 2011;34:410-4.

Ahmadi A, Soori H, Sajjadi H. Modeling of in hospital mortality determinants in myocardial infarction patients, with and without type 2 diabetes, undergoing pharmaco-invasive strategy: the first national report using two approaches in Iran. Diabetes Res Clin Pract. 2015;108:216-22.

Grazuleviciene R, Dulskiene V. Risk factors for heart failure in survivors after first myocardial infarction. Med. 2006;42:810-6.

Velazquez EJ, Francis GS, Armstrong PW, Aylward PE, Diaz R, O’Connor CM, et al. An international perspective on heart failure and left ventricular systolic dysfunction complicating myocardial infarction: the VALIANT registry. Eur Heart J. 2004;25:1911-9.

Chong AY, Rajaratnam R, Hussein NR, Lip GY. Heart failure in a multiethnic population in Kuala Lumpur, Malaysia. Eur J Heart Fail. 2003;5:569-74.

Guo Y, Lip GY, Banerjee A. Heart failure in East Asia. Curr Cardiol Rev. 2013;9:112-2.

Shiba N, Shimokawa H. Chronic heart failure in Japan: implications of the CHART studies. Vasc Health Risk Manag. 2008;4:103-13.

Wang TJ, Larson MG, Levy D, Vasan RS, Leip EP, Wolf PA, et al. Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: the Framingham Heart Study. Circulation. 2003;107:2920-5.

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Published

2017-09-22

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Original Research Articles