Study of diastolic dysfunction in essential hypertension patients in relation to age and duration of treatment
DOI:
https://doi.org/10.18203/2349-3933.ijam20174301Keywords:
Age, Diastolic function, Essential hypertensionAbstract
Background: Hypertension is a major health problem worldwide and its complications have significant socioeconomic impact. The objective of this study was to evaluate diastolic dysfunction (DD) in essential hypertension patients and the influence of age and duration of hypertension on this parameter.
Methods: One hundred essential hypertensive patients (HT) underwent Doppler echocardiography to obtain E/A wave ratio (E/A), atrial deceleration time (ADT), isovolumetric relaxation time (IRT) and Tissue Doppler early diastolic mitral annular velocity (E). All patients were grouped according to age at diagnosis of hypertension and duration of the disease.
Results: A higher prevalence of DD occurred parallel to age and duration of the disease.
Conclusions: DD was prevalent in this hypertensive population, being highly affected by age and DD is observed in incipient stages of hypertensive heart disease, and thus its early detection may help in the risk stratification of hypertensive patients.
References
Dwivedi S, Singh G. Profile of hypertension in elderly subjects. JAPI. 2000:48.
Armstrong WF, Ryan T. Evaluation of left ventricular diastolic function. In: Feigenbaum’s Echocardiography, 7th edition, Philadelphia, Lippincott Williams and Wilkins. 2005;7:159-83.
Zile M, Brutsaert D. New concepts in diastolic dysfunction and diastolic heart failure: Part I. Diagnosis, prognosis, and measurements of diastolic function. Circulation. 2002;105:1387-93.
Oh JK, Seward JB, Tajik AJ. Assessment of diastolic function and diastolic heart failure. The Echo Manual. 3rd edition, New Delhi: Wolters Kluwer Health (India) Pvt. Ltd; 2006:120-142.
Sohn D, Chai L, Lee D, Kim HC, Kim HS, Oh BH, et al. Assessment of mitral annulus velocity by Doppler tissue imaging in the evaluation of left ventricular diastolic function. J Am Coll Cardiol. 1997;30:474-80.
Nikitin N, Witte KK, Clark AL, Cleland JG. Color tissue Doppler-derived long-axis left ventricular function in heart failure with preserved global systolic function. Am J Cardiol. 2002;90:1174-7.
Henein M, Lindqvist P, Francis D, Morner S, Waldenstrom A, Kazzam E. Tissue Doppler analysis of age-dependency in diastolic ventricular behaviour and filling. Eur Heart J. 2002;23:162-71.
Redfield MM, Jacobsen SJ, Burnett JC, Mahoney DW, Bailey KR, Rodeheffer RJ. Burden of systolic and diastolic ventricular dysfunction in the community: appreciating the scope of the heart failure epidemic. JAMA. 2003;289:194-202.
White WB, Schulman P, Dey HM. Effects of age and 24-hour ambulatory blood pressure on rapid left ventricular filling. Am J Cardiol. 1989;63:1343-7.
