Coagulopathy secondary to chicken pox: a case report
Keywords:Chicken pox, Coagulopathy, Healthy adults
Chickenpox often produces a self-limiting disease in children and adolescents. The clinical course is usually mild and complications are rare. The complications that are known to be associated with it are pneumonia, meningitis, myocarditis and nephritis. Severe and disseminated varicella infection with organ dysfunction can also be seen amongst diabetics and immunocompromised patients. However, it is not commonly known that varicella can be life threatening even in immunocompetent adult patients. We present a case of a healthy adult male in which this infection progressed to malignant hemorrhagic disease associated with coagulopathy.
Cvjetković D, Pobor M, Brkić. Primary infection with varicella-zoster virus in risk groups. Med Pregl. 1998;51(3-4):151-4.
Chickenpox (Varicella) Complications. cdc.gov. 16 November 2011.
James J, Watkins L. Hemorrhagic chickenpox associated with disseminated intravascular coagulation Pediatric Research. (1971);5,404-5.
Arvin, A. M “Varicella-Zoster Virus,” Clinical Microbiology Review. 1996,9(3):361-81.
Dinleyici E. Kurugol C, Turel Z. “The Epidemiology and Economic Impact of Varicella-related Hospitalizations in Turkey from 2008 to 2010: A Nationwide Survey during the Pre-Vaccine Era (VARICOMP Study),” Europ. J Pediatr. 2012;171(5):817-25.
Tunbridge AJ, Breuer J, Jeffery KJ. "Chickenpox in adults - clinical management". J Infect. 2008; 57(2):95-102.
Hollenstein U, Thalhammer F, Burgmann H. Disseminated intravascular coagulation (DIC) and rhabdomyolysis in fulminant varicella infection--case report and review of the literature. Infection. 1998;26(5):306-8.
Nguyên P, Reynaud J, Pouzol P, Munzer M, Richard O, François P. Varicella and thrombotic complications associated with transient protein C and protein S deficiencies in children. Eur J Pediatr. 1994;153:646-9.
Kurugöl Z, Vardar F, Ozkinay F, Kavakli K, Ozkinay C. Lupus anticoagulant and protein S deficiency in otherwise healthy children with acute varicella infection. Acta Paediatr. 2000;89(10):1186-9.
Ahamed S, Balkhair A, Krishnan R. Fulminant Varicella Zoster Infection with Multiorgan Involvement-A Case Report. Sultan Qaboos Univ Med J. 2008;8(3):339-43.
Miller HC, Stephan M. Hemorrhagic varicella: a case report and review of the complications of varicella in children. Am J Emerg Med. 1993;11(6):633-8.
De Vas Goonewardane, APN. Malignant chickenpox with coagulopathy in a healthy adult female; a case report and review of literature. Galle Medic J. 2016;20(2),46-7.