Evaluation of clinical profile of febrile thrombocytopenia: an institutional based study
DOI:
https://doi.org/10.18203/2349-3933.ijam20174674Keywords:
Febrile, Fever, ThrombocytopeniaAbstract
Background: Most instances of prolonged fevers are examples of surely understood ailments showing them atypically. Thrombocytopenia is characterized as platelet tally less than 1,50,000/μL. This is because of diminished creation, expanded obliteration, and expanded sequestration in spleen. Hence, we planned the present study to analyse the clinical profile of febrile thrombocytopenia.
Methods: The present study included assessment of clinical profile of febrile thrombocytopenia. A total of 200 subjects were included in the present study. At the time of diagnosis, complete detailed history of all the patients was taken along with thorough clinical examination. Etiologic and clinical data of all the patients was recorded and compiled. All the results will be analysed by SPSS software 16.0.
Results: Out of total 200 cases included in the present study, fifty-two cases were due to viral fever while fifty-seven cases were due to malaria. Jaundice and cough was present in 52 and 58 cases respectively. In fifty five percent of the cases, platelet count was between 50000 to 10000 per cubic mm.
Conclusions: Infectious diseases accounts for most of the cases of febrile thrombocytopenia.
References
Guzman MG, Kouri G. Dengue and dengue hemorrhagic fever in the Americas: Lessons and challenges. J Clin Virol. 2003;27:1-13.
Gibbons RV, Vaughn DW. Dengue: An escalating problem. BMJ. 2002;324:1563-6.
Thomas SJ, Strickman D, Vaughn DW. Dengue epidemiology: Virus epidemiology, ecology, and emergence. Adv Virus Res. 2003;61:235-89.
Pancharoen C, Thisyakom U. Neurological manifestations in dengue patients. Southeast Asian J Trop Med Public Health. 2001;32:341-5.
Murthy JM. Neurological complications of dengue infection. Neurology India. 2010;58:581-4.
Fariz-Safhan MN, Tee HP, Abu Dzarr GA, Sapari S, Lee YY. Bleeding outcome during a dengue outbreak in 2005 in the East-coast region of Peninsular Malaysia: A prospective study. Trop Biomed. 2014;31:270-80.
Wahid SF, Sanusi S, Zawawi MM, Ali RA. A comparison of the pattern of liver involvement in dengue hemorrhagic fever with classic dengue fever. Southeast Asian J Trop Med Public Health. 2000;31:259-63.
Makkar RP, Mukhopadhyay S, Monga A, Monga A, Gupta AK. Plasmodium vivax malaria presenting with severe thrombocytopenia.Braz J Infect Dis. 2002;6:263-5.
Gondhali MP, Vethekar M, Bhangale D, Choudhary K, Chaudhary M, Patrike G. Clinical assessment of fever with thrombocytopenia-A prospective study. International Journal of Medical Research and Health Sciences. 2016;5(1):258-77.
Raikar SR, Kamdar PK, Dabhi AS. Clinical and Laboratory Evaluation of Patients with Fever with Thrombocytopenia. Indian Journal of Clinical Pract. 2013;24(4):360-3.
Fah TS, MMed NAA, Liew CG, Omar K. Clinical Features of Acute Febrile Thrombocytopaenia Among Patients Attending Primary Care Clinics. Malaysian Family Physician: the Official Journal of the Academy of Family Physicians of Malaysia. 2006;1(1):15-8.
Geetha JP, Rashmi MV, Murthy N. Acute Febrile Illness with Thrombocytopenia-a Common Scenario. Ind J Public Health Res Develop. 2015;6(4):163.
Gutthi LP, Vegesna S, Pundarikaksha V, Kolla S, Gundapaneni M, Karimi PK. A study of clinical and lab profile of fever with thrombocytopenia. Internat J Contempt Medic Res. 2017;4(5):1057-61.
Sahil N. Fulara, Nasir Y. Fulara. Dengue shock syndrome: an experience from a tertiary level hospital in Mumbai. Internat J Contemp Medic Res. 2017;4(1):173-5.
Mital R, Agarwal V, Agarwal A. To Assess the relative incidence of and to compare the hemocytological changes in malaria, dengue and typhoid fever or their combination, in children admitted in a tertiary care centre in western UP, India. Internat J Contemp Medic Res. 2016;3(3):718-23.
Kumar PM, Swapna M, Kavitha K, Sudhir U, Sunil HS, Deepak TS. Clinical manifestations and bio-chemical profile of dengue fever in a tertiary care centre. Internat J Contemp Medic Res. 2016;3(3):920-4.
