DOI: http://dx.doi.org/10.18203/2349-3933.ijam20175191

Knowledge, attitude and perception of physicians towards adverse drug reaction (ADR) reporting: a pharmacovigilance study

Anjan Adhikari, Rania Indu, Moumita Ray, Sangita Bhattacharya, Rahul Biswas, Anup Kumar Das

Abstract


Background: Contribution of physicians, in adverse drug reaction (ADR) reporting and monitoring, to develop a global database is enormously significant to ensure safety of medicine. But, in reality, due to lack of awareness among the healthcare providers, under-reporting of suspected ADRs is a major problem, especially in countries like India. Present study aimed to evaluate the knowledge, attitude, and practices (KAP) of the physicians regarding self-reporting of ADR in a tertiary care hospital in Kolkata, West Bengal, India.

Methods: This was a cross-sectional, observational and questionnaire-based study involving physicians of different clinical departments. This questionnaire-based study was conducted to obtain the demography as well as information on knowledge, attitude and perception of physicians towards ADR reporting. Ethical clearance was obtained prior to start the study.

Results: 50 doctors were included in the study after their verbal consent. It was revealed that average time taken to complete the answering of questionnaire by the physicians was 15 minutes. Among the study population (n=50), 54% of the participants were Postgraduate doctors and the rest 46% were graduates. 92% believed that it is necessary and would be beneficial for the patient to report ADRs. 74% also believed that ADR reporting is a professional obligation for doctors.

Conclusions: Present study evaluated that majority of the healthcare professionals had good knowledge and attitude about pharmacovigilance and understand the need for reporting, but the rate of reporting was very low. More interactive training programme is needed to increase the awareness of reporting ADRs by healthcare professionals.

 


Keywords


Adverse drug reaction, Attitude, Knowledge, Pharmacovigilance, Practice, Reporting

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References


Ahmad A, Patel I, Balkrishnan R, Mohanta GP, Manna PK. An evaluation of knowledge, attitude and practice of Indian pharmacists towards adverse drug reaction reporting: A pilot study. Perspectives in Clinical Research. 2013;4(4):204-10.

Olsson S. The role of the WHO Programme for International Drug Monitoring in coordinating worldwide drug safety efforts. Drug Saf. 1998;19(1):1-10.

Ahmad SR. Adverse drug event monitoring at the Food and Drug Administration. J Gen Intern Med. 2003;18(1):57-60.

Lexchin J. Is there still a role for spontaneous reporting of adverse drug reactions? Can Med Assoc J. 2006;174(2):191-2.

Lopez-Gonzalez E, Herdeiro MT, Figueiras A. Determinants of under-reporting of adverse drug reactions: a systematic review. Drug Saf. 2009;32(1):19-31.

Kamtane RA, Jayawardhani V. Knowledge, Attitude and Perception of Physicians towards Adverse Drug Reaction (ADR) Reporting: A Pharmacoepidemiological Study. Asian J Pharm Clin Res. 2012;5(3):210-4.

Rajesh R, Vidyasagar S, Nandakumar K. Highly active antiretroviral therapy induced adverse drug reactions in Indian human immunodeficiency virus positive patients. Pharmacy Practice. 2011;9(1):48-55.

Perlik F, Slanar O, Smid M, Petracek J. Attitude of Czech physicians to adverse drug reaction reporting. Eur J Clin. Pharmacol. 2002;58(5):367-9.

Hasford J, Goettler M, Munter KH, Muller-Oerlinghausen B. Physicians’ knowledge and attitudes regarding the spontaneous reporting system for adverse drug reactions. J Clin. Epidemiol. 2002;55(9):945-50.

Al-Arifi MN et al. Knowledge, Attitude and Perception of Physicians towards Adverse Drug Reaction Reporting at King Khalid University Hospital, Riyadh, Saudi Arabia. Tropic J Pharmaceutic Res. 2015;14(5):907-11.

Gupta P, Udupa A. Adverse Drug Reaction Reporting and Pharmacovigilance: Knowledge, Attitudes and Perceptions amongst Resident Doctors. J Pharm Sci Res. 2011;3(2):1064-69.

Pimpalkhute SA, Jaiswal KM, Sontakke SD, Bajait CS, Gaikwad A. Evaluation of awareness about pharmacovigilance and adverse drug reaction monitoring in resident doctors of a tertiary care teaching hospital. Indian J Med Sci. 2012;66(3):55-61.

Reddy VL, Pasha SKJ, Rathinavelu M, Reddy YP. Assessment of Knowledge, Attitude and Perception of Pharmacovigilance and Adverse Drug Reaction (ADR) Reporting among the Pharmacy Students in South India. IOSR J Pharmacy Biologic Sci. 2014;9(2):34-43.

Gupta SK, Nayak RP, Shivaranjani R, Vidyarthi SK. A questionnaire study on the knowledge, attitude, and the practice of pharmacovigilance among the healthcare professionals in a teaching hospital in South India. Perspect Clin Res. 2015;6(1):45-52.

Datta S, Sengupta S. An evaluation of knowledge, attitude, and practice of adverse drug reaction reporting in a tertiary care teaching hospital of Sikkim. Perspectives in Clinical Res. 2015;6(4):200-206.

Desai CK, Iyer G, Panchal J, Shah S, Dikshit RK. An evaluation of knowledge, attitude, and practice of adverse drug reaction reporting among prescribers at a tertiary care hospital. Perspectives in Clinical Research. 2011;2(4);129-36.

Kalaiselvan V, Prasad T, Bisht A, Singh S, Singh GN. Adverse drug reactions reporting culture in Pharmacovigilance Programme of India. Ind J Medic Res. 2014;140(4):563-4.

Khan SA, Goyal C, Chandel N, Rafi M. Knowledge, attitudes, and practice of doctors to adverse drug reaction reporting in a teaching hospital in India: An observational study. J Natural Sci Biol Medic. 2013;4(1):191-6.