Acute pancytopenia secondary to hemophagocytic syndrome due to plasmodium vivax malaria with chloroquine treatment failure: case report


  • Rajnish Kumar Department of Medicine, Lifeaid Medical centre, Gurgaon, Haryana, India
  • Avantika Sharma Department of Gynaecology, Lifeaid Medical centre, Gurgaon, Haryana, India



Artesunate therapy, Chloroquine, Hemophagocytosis, Malaria, Pancytopenia, Plasmodium vivax resistance


Pancytopenia as a manifested complication of plasmodium vivax malaria is extremely rare and mainly reported with plasmodium falciparum. We report a 29-year old Indian pregnant female who lives in rural area of Haryana (northern India) and presented with a two-week long history of intermittent fever, chills and rigor. She was found to have spleenomegaly, pancytopenia, hyperferrtinemia with positive peripheral blood smear for plasmodium vivax. not responding to oral chloroquine. The patient had a full recovery from pancytopenia with artesunate therapy.


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