Morphologic features in cystic lesions of pancreas-a retrospective analysis
DOI:
https://doi.org/10.18203/2349-3933.ijam20180083Keywords:
Cystic, Lesions, Neoplasms, PancreasAbstract
Background: Cystic lesions of pancreas consist of a broad spectrum of reactive, benign and malignant conditions. The most common among cystic pancreatic lesions is pseudocyst of pancreas. Cystic tumours of pancreas are less common than solid one’s accounting for less than 1% according to some studies. Literature review showed only a few extensive studies on cystic lesions of pancreas, especially from South India.
Methods: Our research is a descriptive histopathological analysis of 38 cases of cystic lesions of pancreas, done in the department of pathology of our institution, over a period of 5 years.
Results: We received a total of 38 cases of cystic lesions of pancreas. The age distribution ranged from 17 to 77 years. Male to female ratio was 24: 14. There were neoplastic and non neoplastic entities. Pseudocyst of pancreas was the most common cystic lesion (12 cases). Benign neoplasms included serous cystadenomas, mucinous cystadenomas and lymphangiomas. Ductal adenocarcinomas with cystic degeneration and adenocarcinomas with mucinous component were some of the malignant cystic lesions.
Conclusions: Cystic pancreatic lesions accounted for 24% of all the pancreatic lesions received in our institution during the period of this study. 24 cases (63%) were benign lesions and 14 cases (37 %) were malignant. Though cystic lesions of pancreas especially neoplasms are less frequent than solid neoplasms, it is important to study their diagnostic features since the management differs. Imaging studies may be similar in some cystic lesions. A proper clinicoradiological correlation and detailed investigational work up will aid in the correct diagnosis.
References
Dietrich CF, Jenssen C. Benign and malignant cystic tumors of the pancreas. In: Dietrich CF, editor. Endoscopic ultrasound-an introductory manual and atlas. 1st ed. New York:Thieme;2006:208-29.
Kloppel G, Maillet B. Pseudocysts in chronic pancreatitis:a morphological analysis of 57 resection specimens and 9 autopsy pancreata. Pancreas. 1991;6:266-74.
Khan A, Khosa F, Eisenberg RL. Cystic lesions of the pancreas. AJR Am J Roentgenol. 2011;196(6):W668-77.
Adsay NV. Cystic lesions of the pancreas. Mod Pathol. 2007:20:71-93.
Pulvirenti A, Marchegiani G, Malleo G, Borin A, Allegrini V, Bassi C, et al. Cystic Neoplasm of the Pancreas. Ind J Surg. 2015;77(5):387-92.
Karoumpalis I, Christodoulou DK. Cystic lesions of the pancreas. Annals of Gastroenterology: Quarterly Publication Hellenic Soci Gastroenterol. 2016;29(2):155-61.
Demos TC, Posniak HV, Harmath C, Olson MC, Aranha G. Cystic lesions of the pancreas. AJR Am J Roentgenol. 2002;179:1375-88.
Wilentz RE, Albores-Saavedra J, Zahurak M, Talamini MA, Yeo CJ, Cameron JL, Hruban RH. Pathologic examination accurately predicts prognosis in mucinous cystic neoplasms of the pancreas. Ame J Surg Pathol. 1999;23(11):1320.
Cicy PJ, Sansho EU, Lekshmidevi P, Umman P, Varghese S, Kurian JS. Giant cystic lymphangioma of pancreas-a rarity. World J Pathol. 2014;4:72-6.
Paik KY, Choi SH, Heo JS, Choi DW. Solid tumors of the pancreas can put on a mask through cystic change. World J Surg Oncol. 2011;9:79.
Farrell JJ. Prevalence, Diagnosis and management of pancreatic cystic neoplasms: current status and future directions. Gut and Liver. 2015;9(5):571-89.
