Pattern of dermatologic manifestations in polycystic ovarian disease cases from a tertiary care hospital

Authors

  • Preeti Jain Department of Pathology, FH Medical College, NH-2, Tundla, Uttar Pradesh, India
  • Shailendra Kumar Jain Department of Skin and VD, FH Medical College, NH-2, Tundla, Uttar Pradesh, India
  • Abhishek Singh Department of Community Medicine, SHKM Govt. Medical College, Mewat, Haryana, India
  • Shewtank Goel Department of Microbiology, Teerthanker Mahaveer Medical College, Moradabad, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20180084

Keywords:

Acne, Hirsutism, Hyperandrogenism, Polycystic ovary syndrome

Abstract

Background: Dermatologists often play a significant role in its management. Cutaneous features of hyperandrogenism in Polycystic ovarian syndrome (PCOS) have varied presentation. Aim of this study was the pattern of dermatologic manifestations in polycystic ovarian disease in northern Indian females.

Methods: Patients registering for treatment of polycystic ovarian disease at Dermatology outpatients department during April 2016 to March 2017 formed the study population. Residents interviewed the study subjects at the OPD. General physical examination, systemic examination, breast and pelvic examination, along with detailed dermatological examination were conducting after taking the history. Hormonal analysis was performed after an overnight fasting using enzyme immunoassay.

Results: FSH and LH levels were 5.05±1.86 IU/L and 8.14±5.21 IU/L respectively. Testosterone levels were found to be 61.01±25.32 ng/dl. DHEAS levels among them were 130.05±41.21μg/dl. Two commonest cutaneous manifestations were hirsutism and acne seen in 83.8% and 59.5% of subjects. Female pattern hair loss was seen in 45.6% females. Three most frequent hormonal abnormalities noted in our study subjects were raised L/H ratio, testosterone and LH levels seen in approximately 45%, 35% and 21% cases.

Conclusions: The cutaneous manifestations of PCOS reserve a major role in its management by dermatologists. A lifestyle modification along with systemic treatment remains mainstay of treatment. Monitoring for the foreseen cardiovascular risks should start early to downgrade the morbidity.

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Published

2018-01-18

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Original Research Articles