A variant of Kounis syndrome due to diclofenac sodium

Authors

  • Arun Kumar Alagesan Department of Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India
  • Kannan R. Department of Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India
  • Tirumalasetty Sriharsha Department of Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India
  • Vikrannth V. Department of Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India
  • Raghav J. Department of Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India
  • Vinod Raghavan Department of Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India
  • Monika Reddy Department of Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20230065

Keywords:

Drug induced coronary vasospasm, Anaphylaxis, Kounis syndrome

Abstract

Kounis syndrome is an acute coronary syndrome of varying degrees induced by allergic or anaphylactic reaction leading to coronary vasospasm or atheromatous plaque erosion or rupture or global myocardial hypoperfusion occurring as a result of systemic vasodilation and decreased venous return in context of anaphylaxis. We reported a case of 33-year-old female who presented to emergency department in an irritable state with complaints of nausea, vomiting, abdominal pain, breathlessness and generalized itching which developed secondary to administration of diclofenac injection by intra muscular (IM) route. On evaluation, echocardiography revealed global LV systolic dysfunction. The patient was successfully treated with continuous noradrenaline infusion, fluid resuscitation and other supportive measures with repeat echocardiography revealing normal LV systolic function.

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Author Biography

Kannan R., Department of Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India

 

 

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Published

2023-01-23

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Case Reports